Glass vial labeled Compounded Semaglutide for RX weight loss with a purple cap on a light purple background.

Clear vial labeled Compounded Semaglutide with lavender cap for RX weight loss.

Graph showing Polly members lose more weight over six months than diet and exercise alone.

Woman smiling during a video call with a male doctor on her laptop at home.

Hand holding phone showing medication tracking app for Semaglutide with progress graph and dosage info.

Hand holding phone showing medication tracking app with Tirzepatide details and a progress bar chart.

Compounded Semaglutide

A once-weekly injection, through Polly's weight loss program.

$135

Pay over time with

Provider-reviewed · Ships from licensed U.S. pharmacies

Lose up to 21.5% body weight¹

No membership or hidden fees

Same price at every dose

Next day shipping included

Check if I’m eligible

Complete a quick online assessment

Clinician support included

No insurance required

Real results from real customers

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What’s included with your treatment?

Your plan may include provider review, prescription treatment if approved, ongoing support, and discreet shipping directly to your door.

How much weight can I lose?

Results vary by person. Your progress depends on your treatment plan, lifestyle, consistency, and your provider’s guidance.

Are there any side effects?

Some people may experience side effects. A licensed provider will review your health history and help determine if treatment is appropriate for you.

How quickly will I see result?

Everyone responds differently. Some people may start noticing changes within the first few weeks, while others may take longer.

Where does it ship from?

If approved, your treatment is shipped discreetly from a licensed pharmacy directly to your door.

What’s included

What’s included with your treatment?

Everything you need to start with confidence, if prescribed by a licensed provider.

Online assessment

Answer a few health questions in minutes to check your eligibility.

Provider review

A licensed provider reviews your health information and goals.

Medication if prescribed

Compounded Semaglutide is prescribed only if medically appropriate.

Ongoing support

Get guidance for treatment questions, side effects, and next steps.

Free shipping

Discreet, fast delivery from licensed U.S. facilities.

No insurance required

Transparent pricing with no membership or hidden fees.

Real results supported by science

Sustainable weight loss

Our treatments are designed to support consistent, healthy weight loss over time.

Graph showing weight loss over 6 months; Polly's curve drops faster than diet and exercise.

improved metabolic health

87% reported reduced appetite. Improved glucose stability within weeks.

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Based on clinical research and patient testimonials.

Check if I’m eligible

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How it works

How to get started

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Take your online assessment

Answer a few questions about your health and goals.

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Get a recommendation

A provider reviews your info and recommends a plan.

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Delivered to your door

If approved, your treatment is shipped discreetly to you.

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Support at every step of your treatment

From your online visit to ongoing care, Polly helps guide your weight loss journey with provider support and progress tools.

Provider review before treatment

Ongoing support for treatment questions

Guidance for side effects and next steps

Progress tracking throughout your journey

Polly’s Switch Commitment

Already on treatment? Switch with Polly

Take our free assessment

Check your eligibility with our 1 minute online assessment

Get a recommendation

Find the weight loss treatment plan for you

Delivered to your door

Get your treatments delivered discreetly for free

What to expect

Your weight loss journey

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0 to 3 months

Getting started

Your provider reviews your health profile and treatment plan. As your body adjusts, you may begin noticing changes in appetite, portions, and daily habits.

Glossy 3D illustration of a square bathroom scale with needle pointing at middle.

3 to 6 months

Building momentum

With ongoing support, your provider may adjust your plan if needed. Many patients use this stage to build more consistent routines around nutrition, movement, and medication.

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6 to 12+ months

Long-term progress

Your treatment journey continues with guidance designed to help you maintain progress, manage questions, and stay supported over time.

Frequently asked questions

What’s included with your treatment?

Your plan may include provider review, prescription treatment if approved, ongoing support, and discreet shipping directly to your door.

How much weight can I lose?

Results vary by person. Your progress depends on your treatment plan, lifestyle, consistency, and your provider’s guidance.

Are there any side effects?

Some people may experience side effects. A licensed provider will review your health history and help determine if treatment is appropriate for you.

How quickly will I see result?

Everyone responds differently. Some people may start noticing changes within the first few weeks, while others may take longer.

Where does it ship from?

If approved, your treatment is shipped discreetly from a licensed pharmacy directly to your door.

Check if you’re eligible in minutes

Quick online assessment. No commitment required.

Check if I’m eligible

The products offered by Polly are compounded medications prepared by licensed compounding pharmacies. These formulations are not approved by the U.S. Food and Drug Administration (FDA) and have not undergone clinical trials to evaluate their safety, efficacy, or therapeutic equivalence to any FDA-approved medications.
‍
They are not intended to diagnose, treat, cure, or prevent any disease and are not substitutes for FDA-approved medications such as MOUNJARO®, ZEPBOUND™, Wegovy®, or Ozempic®.
‍
Any claims regarding effectiveness, safety, or weight loss benefits relate only to general mechanisms of the active ingredients (e.g., tirzepatide or semaglutide) and do not pertain to Polly's specific compounded formulations.

These products are not approved for cosmetic weight loss and should only be used under the supervision of a licensed healthcare provider. By purchasing or using these products, you acknowledge and accept these terms.

Check if I’m eligible